Publications
Selected Publications before 2018
Rajman M, Metge F, Fiore R, Khudayberdiev S, ... Dieterich C, Schratt G. (2017) A microRNA-129-5p/Rbfox crosstalk coordinates homeostatic downscaling of excitatory synapses. EMBO J. 36(12): 1770-1787.
Rajman M and Schratt G. (2017) MicroRNAs in neural development and disease: from master regulators to fine-tuners. Development, 144(13):2310-2322.
Brenes JC, Lackinger M, Höglinger GU, Schratt G, Schwarting RK, Wöhr M. (2016) Differential effects of social and physical environmental enrichment on brain plasticity, cognition, and ultrasonic communication in rats. J Comp Neurol., 524(8):1586-607.
Forstner AJ, ..., Schratt G, Nöthen MM. Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder. Transl Psychiatry 2015 Nov 10;5:e678. doi: 10.1038/tp.2015.159.
Störchel PH, Thümmler J, Siegel G, Zampa F, Sumer S, Schratt G. (2015) A large scale functional screen identifies Nova1 and Ncoa3 as regulators of neuronal miRNA function. EMBO J 34(17):2237-54.
Olde Loohuis NF, Ba W, Stoerchel PH, Kos A, Jager A, Schratt G, Martens GJ, van Bokhoven H, Nadif Kasri N, Aschrafi A. (2015) MicroRNA-137 Controls AMPA-Receptor-Mediated Transmission and mGluR-Dependent LTD. Cell Rep. 11(12):1876-84.
Valluy J, Bicker S, Aksoy-Aksel A, Lackinger M, Sumer S, Fiore R, Wüst T, Seffer D, Metge F, Dieterich C, Wöhr M, Schwarting R, Schratt G. (2015) A coding-independent function of an alternative Ube3a transcript during neuronal development, Nature Neuroscience 18(5):666-73.
Peykov S, Berkel S, Schön M, Weiss K, Weiss B, Schratt G, Noethen M, Boeckers TM, Rietschel M, Rappold GA. (2015) Identification and functional characterization of rare SHANK2 variants in schizophrenia, Mol. Psychiatry, 20(12):1489-98.
Fiore R, Rajman M, Schwale C, Bicker S, Antoniou A, Bruehl C, Draguhn A, Schratt G. (2014) miR-134-dependent regulation of Pumilio2 is necessary for homeostatic synaptic depression, EMBO J, 33(19):2231-46.
Aksoy-Aksel A, Zampa F, Schratt G. (2014) microRNAs and synaptic plasticity – a mutual relationship. Phil. Trans. R. Soc. Lond. B,369(1652).
Khudayberdiev S, Zampa F, Rajman M and Schratt G (2013) A comprehensive characterization of the nuclear microRNA repertoire of post-mitotic neurons. Front. Mol. Neurosci. 6: 43.
Bicker S, Khudayberdiev S, Weiss K, Zocher K, Baumeister S, Schratt G. (2013) The DEAD-box helicase DHX36 mediates dendritic transport of the neuronal precursor-microRNA-134. Genes Dev 27:991-996
Saba, R., Störchel, P.H., Aksoy-Aksel, A., Kepura, F., Lippi, G., Plant, T.D. and Schratt, G. (2012) The dopamine-regulated microRNA, miR-181a, controls GluA2 surface expression in hippocampal neurons. Mol Cell Biol. 32(3):619-32.
Siegel, G., Saba R. and Schratt G., (2011) microRNAs in neurons: manifold regulatory roles at the synapse. Curr Opin Genet Dev. 21(4):491-7.
Christensen, M., Larsen, L.A., Kauppinen, S. & Schratt G. (2010) Recombinant adeno-associated virus-mediated microRNA delivery into the postnatal mouse brain reveals a role for miR-134 in dendritogenesis in vivo. Frontiers in Neural Circuits,3:16.
Schratt, G. (2009) microRNAs at the synapse. Nat Rev Neurosci. 10(12): 842-9.
Schratt G. (2009) Fine-tuning neural gene expression with microRNAs. Curr. Op. Neurobiol., 19(2):213-9.
Siegel G.*, Obernosterer G.*, Fiore R., Oehmen, M., Bicker, S., Christensen M., Khudayberdiev, S., Leuschner, P., Busch, C., Kane, C., Hübel K., Dekker, F., Hedberg, C., Rengarajan, B., Drepper, C., Waldmann H., Kauppinen S., Greenberg M.E., Draguhn, A., Rehmsmeier M., Martinez J. and Schratt G. (2009) A functional microRNA screen implicates miR-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. Nature Cell Biology, 11(6):705-716.
Fiore R.*, Khudayberdiev S.*, Christensen M., Siegel G., Flavell S., Kim T.K., Greenberg M.E. and Schratt G. (2009) Mef2-dependent activation of the miR-379-410 cluster promotes dendritic outgrowth by fine-tuning protein levels of the translational repressor Pumilio2. EMBO J.18;28(6):697-710.
Schratt G, Tuebing F, Nigh EA, Kane CG, Sabatini ME, Kiebler M and Greenberg ME. (2006) A brain-specific microRNA regulates dendritic spine development. Nature, 439(7074):283-9.