miRNAs in brain physiology/pathology

In this project, we are using genetically modified mouse models to explore the function of specific miRNAs during brain development and in adult behavior. We are particularly interested in potential cognitive and social impairments in these mice with links to neurodevelopmental (e.g. autism) and neuropsychiatric (e.g. schizophrenia, depression) disorders. Furthermore, we want to use these mouse models to explore the role of microRNA-dependent gene regulatory networks in stress resilience.